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CHIP Polyclonal Antibody, 20ul In vitro Transcription and cell proliferation

SKU: 14216892046

4.4
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CHIP Polyclonal Antibody, 20ul In vitro Transcription and cell proliferationThis gene encodes a protein containing tetratricopeptide repeat and a U box that functions as a ubiquitin ligase cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

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Description

and cell proliferation

Represses the ligand-dependent transcriptional activation function of ESR2 (PubMed: 20074560)

RUNX3 (runt related transcription factor 3) encodes a member of the runt domain-containing family of transcription factors

specifically myogenesis

Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines

CHIP Polyclonal Antibody, 20ul In vitro Transcription and cell proliferationThis gene encodes a protein containing tetratricopeptide repeat and a U box that functions as a ubiquitin ligase cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

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