Rat Multidrug and Toxin Extrusion Protein 1, SLC47A1 ELISA Kit, 96T Monoclonal Antibodies In the cytoplasm functions as

In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses

This protein also participates in the TGF-beta signaling pathway

A secreted form and a membrane-anchored form of betacellulin bind to multiple different EGF receptors

supporting a higher centrifugal speed

including TNF secretion by monocytes (PubMed: 11276205)

Rat Multidrug and Toxin Extrusion Protein 1, SLC47A1 ELISA Kit, 96T Monoclonal Antibodies In the cytoplasm functions asSolute transporter for tetraethylammonium (TEA), cimetidine, metformin, guanidine, N methylnicotinamide (NMN) and also the zwitterionic cephalosporin cephalexin. Not a transporter for 1 methyl 4 phenylpyridinium (MPP), procainamide, creatinine, guanidine, p aminohippurate (PAH) and the anionic cephalosporin cefalozin. MPP transport activity has been observed in PubMed: 16928787 and PubMed: 17047166 and may contradict results observed in PubMed: