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Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions PTM:Sumoylated

SKU: 1356873434

4.6
PLN97.20 PLN135.20

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Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions PTM:SumoylatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

PTM:Sumoylated

Binds chylomicrons

May regulate B-cell antigen receptor-mediated signaling

Changes in expression of this gene have been linked to prostate cancer

SERPINB5 is a Protein Coding gene

Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions PTM:SumoylatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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