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JIK Polyclonal Antibody, 50ul Plasma Alternative splicing of PLAT results

SKU: 13456998426

4.3
SEK162.00 SEK190.00

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JIK Polyclonal Antibody, 50ul Plasma Alternative splicing of PLAT resultsTAOK3 is a Protein Coding gene. Serine threonine protein kinase TAO3 acts as a regulator of the p38 MAPK14 stress activated MAPK cascade and of the MAPK8 JNK cascade. Acts as an activator of the p38 MAPK14 stress activated MAPK cascade. In response to DNA damage, involved in the G2 M transition DNA damage checkpoint by activating the p38 MAPK14 stress activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases.

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Description

Alternative splicing of PLAT results in multiple transcript variants

and antagonizes glucocorticoid-stimulated gene transcription

This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage| which may be required for its phosphorylation

Gene Ontology (GO) annotations related to this gene include alpha-tubulin binding

These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain

JIK Polyclonal Antibody, 50ul Plasma Alternative splicing of PLAT resultsTAOK3 is a Protein Coding gene. Serine threonine protein kinase TAO3 acts as a regulator of the p38 MAPK14 stress activated MAPK cascade and of the MAPK8 JNK cascade. Acts as an activator of the p38 MAPK14 stress activated MAPK cascade. In response to DNA damage, involved in the G2 M transition DNA damage checkpoint by activating the p38 MAPK14 stress activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases.

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