AES Polyclonal Antibody, 100ul Mammalian Expression Disruption of septin function disturbs

Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells

|tissue specificity:Abundantly expressed in heart and pancreas

TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs

Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling

Reduced expression and rearrangement of this gene have been detected in various cancers

AES Polyclonal Antibody, 100ul Mammalian Expression Disruption of septin function disturbsThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms