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Phospho-BRCA1 (S1524) Polyclonal Antibody, 100ul Gene Synthesis More than 80 different mutations

SKU: 1251157189

4.5
USD123.75 USD173.75

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Phospho-BRCA1 (S1524) Polyclonal Antibody, 100ul Gene Synthesis More than 80 different mutationsBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

More than 80 different mutations in this gene have been reported

its expression is not supported by other experimental evidence

Multiple transcript variants encoding different isoforms have been found for SLC39A4

5 mL is RCF 30

Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented

Phospho-BRCA1 (S1524) Polyclonal Antibody, 100ul Gene Synthesis More than 80 different mutationsBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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