Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Genetic variation at this locus

Genetic variation at this locus has been associated with a range of behavioral phenotypes

Mutations in SMC1A result in Cornelia de Lange syndrome

although the full-length nature of only two has been determined

tissue specificity:Expressed in spleen

Localizes to centrosomes

Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Genetic variation at this locusHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.