Integrin Beta3 Polyclonal Antibody, 20ul[BT-AP04588] Miscellaneous also designated Dermatomyositis associated with

also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1)

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Alternatively spliced transcript variants encoding different isoforms exist

and it is located in a region that is commonly deleted in a variety of malignancies

This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece

Integrin Beta3 Polyclonal Antibody, 20ul[BT-AP04588] Miscellaneous also designated Dermatomyositis associated withIntegrin beta 3 encoded by ITGB3 is the integrin beta chain beta 3. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling.