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Flk-1 Polyclonal Antibody, 50ul[BT-AP03269] Sealing Film Male mice which lack TSSK6

SKU: 11921583804

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Flk-1 Polyclonal Antibody, 50ul[BT-AP03269] Sealing Film Male mice which lack TSSK6VEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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Description

Male mice which lack TSSK6 encoding a highly similar protein are sterile and have morphologically abnormal sperm

it is thought to play a role in nitric oxide and polyamine metabolism

which function in the synthesis of ribosomal RNA precursors and small RNAs

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin

Multiple different transcript variants are generated by alternate splicing

Flk-1 Polyclonal Antibody, 50ul[BT-AP03269] Sealing Film Male mice which lack TSSK6VEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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