NUCKS Polyclonal Antibody, 20ul Cell Culture Differential sialylation of cell surface

Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells

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cell adhesion and T-cell regulation

In addition to its role in regulating the later stages of terminal differentiation of keratinocytes

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NUCKS Polyclonal Antibody, 20ul Cell Culture Differential sialylation of cell surfaceNUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1) encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin dependent kinases, two putative nuclear localization signals, and a basic DNA binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.