HNK-1ST Polyclonal Antibody, 100ul Drug Development and Evaluation Two transcript variants encoding the

Two transcript variants encoding the same protein have been identified

Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections

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This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis| which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI)

The protein encoded by this gene is a member of the Mastermind-like family of proteins

HNK-1ST Polyclonal Antibody, 100ul Drug Development and Evaluation Two transcript variants encoding theCarbohydrate sulfotransferase 10 encoded by CHST10 transfers sulfate to the C 3 hydroxyl of terminal glucuronic acid of protein and lipid linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer 1 (HNK 1) glycan; HNK 1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.