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ITSN2 Polyclonal Antibody, 50ul Endonucleases & Exonucleases disulfide-linked

SKU: 11305913893

4.4
USD162.00 USD182.00

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ITSN2 Polyclonal Antibody, 50ul Endonucleases & Exonucleases disulfide-linkedThis gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants

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Description

disulfide-linked

The inner- and outer-arm dyneins

Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome

Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases

and higher expression of ITGA5 may be correlated with shorter survival time in lung cancer patients

ITSN2 Polyclonal Antibody, 50ul Endonucleases & Exonucleases disulfide-linkedThis gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants

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