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OSBP2 Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging Expansion of the polyglutamine tract

SKU: 10875185892

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OSBP2 Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging Expansion of the polyglutamine tractThe protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol binding region. It binds oxysterols such as 7 ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease)

Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions

Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction

4 cm² of growth area and made of GPPS material

Zinc finger MYND-type containing 8 encoded by ZMYND8 is a receptor for activated C-kinase (RACK) protein

OSBP2 Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging Expansion of the polyglutamine tractThe protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol binding region. It binds oxysterols such as 7 ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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