BEX2 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction The gene is part of

The gene is part of a cluster of MMP genes which localize to chromosome 11q22

Himmelfarb et al

binds DNA as a dimer

Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation

cytoskeletal reorganization

BEX2 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction The gene is part ofThis gene belongs to the brain expressed X linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA binding complex that recognizes the E box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti proliferative effect