RPB7 Polyclonal Antibody, 20ul Sampling Tubes the gene is expressed in

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the Catalytic activity is acquired

which binds to the core promoter to position the polymerase properly

Transcript variants utilizing alternative polyadenylation signals exist for this CTSG

A processed pseudogene of this gene has been found on chromosome 1

RPB7 Polyclonal Antibody, 20ul Sampling Tubes the gene is expressed inThis gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.