IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis Deficiency of this enzyme results

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

While the primary structure of transglutaminases is not conserved

Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

AASS encodes a bifunctional enzyme (aminoadipate-semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis Deficiency of this enzyme resultsIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.